Goossens Alain

Goossens Alain - Group leader
Joined the group in 1993

My bioresume

I have obtained my Master in Biology-Plant Biotechnology at Ghent University (1992) and my PhD under the supervision of Geert Angenon and Marc Van Montagu at the Laboratory of Genetics, Ghent University (Belgium, 1998), studying plant seed storage protein synthesis. During my PhD, I have also been a visiting researcher at CIAT in Cali (Colombia) in the group of Cesar Cardona. After obtaining my PhD degree, I moved to the lab of Ramon Serrano at the IBMCP-UPV in Valencia (Spain) as a Marie Curie EU postdoctoral fellow to work for 2 years on yeast salt tolerance. I returned to Belgium afterwards and started my own research group within the VIB-UGent Center for Plant Systems Biology in 2003, focusing on phytohormone signaling, gene discovery in plant specialized metabolism and metabolic engineering. My current research aspires to understand jasmonate signaling in model, crop and medicinal plants and unravel the mechanisms that steer plant metabolism in fitness programs to find novel tools for plant metabolic engineering and synthetic biology. I have been appointed as a Full Professor at Ghent University in 2015 and senior Full Professor in 2022. I have been mentoring over 45 master students, 35 PhD students and 25 postdoctoral researchers. Over 10 of my alumni have acquired leading academic positions as group leaders, professors or managers of core facilities at universities in Belgium and abroad. Since 2015 I have been included in the Thomson Reuters list of ISI Highly Cited Researchers in Plant & Animal Sciences. In 2020 I have been elected as an EMBO member.

195. A tomato B-box protein regulates plant development and fruit quality through the interaction with PIF4, HY5, and RIN transcription factors

Lumi Shiose, Juliene dos Reis Moreira, Bruno Silvestre Lira, Gabriel Ponciano, Gabriel Gómez-Ocampo, Raquel Tsu Ay Wu, José Laurindo dos Santos Júnior, Nikolaos Ntelkis, Elke Clicque, Maria José Oliveira, Greice Lubini, Eny Iochevet Segal Floh, javier botto, Marcelo José Pena Ferreira, Alain Goossens, Luciano Freschi, Magdalena Rossi

(2024) - Journal of Experimental Botany

DOI
194. Exploring the potential role of four Rhizophagus irregularis nuclear effectors: opportunities and technical limitations

María Victoria Aparicio Chacón, Sofía Hernández Luelmo, Viktor Devlieghere, Louis Robichez, Toon Leroy, Naomi Stuer, Annick De Keyser, Evi Ceulemans, Alain Goossens, Sofie Goormachtig, Judith Van Dingenen

(2024) - Frontiers in Plant Science

DOI
193. Unlocking saponin biosynthesis in soapwort

Seohyun Jo, Amr El-Demerdash, Charlotte Owen, Vikas Srivastava, Dewei Wu, Shingo Kikuchi, James Reed, Hannah Hodgson, Alex Harkess, Shengqiang Shu, Christopher Plott, Jerry Jenkins, Melissa Williams, Lori-Beth Boston, Elia Lacchini, Tongtong Qu, Alain Goossens, Jane Grimwood, Jeremy Schmutz, James Leebens-Mack, Anne Osbourn

(2024) - Nature Chemical Biology

DOI
192. Cell type-specific control and post-translational regulation of specialized metabolism: opening new avenues for plant metabolic engineering

Nikolaos Ntelkis, Alain Goossens, Krešimir Šola

(2024) - Current Opinion in Plant Biology

DOI
191. Structural and functional diversity in plant specialized metabolism signals and products: The case of oxylipins and triterpenes

Elia Lacchini, Jhon Venegas-Molina, Alain Goossens

(2023) - Current Opinion in Plant Biology

DOI
190. Engineering the plant metabolic system by exploiting metabolic regulation

Sara Selma, Nikolaos Ntelkis, Trang Hieu Nguyen, Alain Goossens

(2023) - The Plant Journal

DOI
189. Identification and characterization of CYP71 subclade cytochrome P450 enzymes involved in the biosynthesis of bitterness compounds in Cichorium intybus.

De Bruyn C, Ruttink T, Lacchini E, Rombauts S, Haegeman A, De Keyser E, Van Poucke C, Desmet S, Jacobs TB, Eeckhaut T, Goossens A, Van Laere K

(2023) - Frontiers in plant science

DOI
188. A redundant transcription factor network steers spatiotemporal Arabidopsis triterpene synthesis.

Nguyen TH, Thiers L, Van Moerkercke A, Bai Y, Fernández-Calvo P, Minne M, Depuydt T, Colinas M, Verstaen K, Van Isterdael G, Nützmann HW, Osbourn A, Goossens A

(2023) - Nature plants

DOI
187. The saponin bomb: a nucleolar-localized β-glucosidase hydrolyzes triterpene saponins in Medicago truncatula.

Lacchini E, Erffelinck ML, Mertens J, Marcou S, Molina-Hidalgo FJ, Tzfadia O, Venegas-Molina J, Cárdenas PD, Pollier J, Tava A, Bak S, Höfte M, Goossens A

(2023) - The New phytologist

DOI
186. The Non-JAZ TIFY Protein TIFY8 of Arabidopsis thaliana Interacts with the HD-ZIP III Transcription Factor REVOLUTA and Regulates Leaf Senescence.

Andrade Galan AG, Doll J, Saile SC, Wünsch M, Roepenack-Lahaye EV, Pauwels L, Goossens A, Bresson J, Zentgraf U

(2023) - International journal of molecular sciences

DOI
185. Rhizogenic Agrobacterium protein RolB interacts with the TOPLESS repressor proteins to reprogram plant immunity and development.

Gryffroy L, Ceulemans E, Manosalva Pérez N, Venegas-Molina J, Jaramillo-Madrid AC, Rodrigues SD, De Milde L, Jonckheere V, Van Montagu M, Goossens A

(2023) - Proceedings of the National Academy of Sciences of the United States of America

DOI
184. Cataloguing Protein Complexes In Planta Using TurboID-Catalyzed Proximity Labeling.

Gryffroy L, De Ryck J, Jonckheere V, Goormachtig S, Goossens A, Van Damme P

(2023) - Methods in molecular biology (Clifton, N.J.)

DOI
183. Identification of Plant Protein-Metabolite Interactions by Limited Proteolysis-Coupled Mass Spectrometry (LiP-MS).

Venegas-Molina J, Van Damme P, Goossens A

(2023) - Methods in molecular biology (Clifton, N.J.)

DOI
182. Within and beyond organelle engineering: strategies for increased terpene production in yeasts and plants

Ana Cristina Jaramillo-Madrid, Elia Lacchini, Alain Goossens

(2022) - Current Opinion in Green and Sustainable Chemistry

DOI
181. SlKIX8 and SlKIX9 are negative regulators of leaf and fruit growth in tomato

Gwen Swinnen, Jean-Philippe Mauxion, Alexandra Baekelandt, Rebecca De Clercq, Jan Van Doorsselaere, Dirk Inzé, Nathalie Gonzalez, Alain Goossens, Laurens Pauwels

(2022) - Plant Physiology

DOI
180. Jasmonate: A hormone of primary importance for plant metabolism

Trang Hieu Nguyen, Alain Goossens, Elia Lacchini

(2022) - Current Opinion in Plant Biology

DOI
179. Engineering a highly sensitive biosensor for abscisic acid in mammalian cells

Seo Woo Kim, Kübra Alci, Femke Van Gaever, Yasmine Driege, Keylla Bicalho, Geert Goeminne, Claude Libert, Alain Goossens, Rudi Beyaert, Jens Staal

(2022) - FEBS Letters

DOI
178. Touch signaling and thigmomorphogenesis are regulated by complementary CAMTA3- and JA-dependent pathways

Essam Darwish, Ritesh Ghosh, Abraham Ontiveros-Cisneros, Huy Cuong Tran, Marcus Petersson, Liesbeth De Milde, Martyna Broda, Alain Goossens, Alex Van Moerkercke, Kasim Khan, Olivier Van Aken

(2022) - Science Advances

DOI
177. Corrigendum: Interference between ER stress-related bZIP-type and jasmonate-inducible bHLH-type transcription factors in the regulation of triterpene saponin biosynthesis in Medicago truncatula.

Ribeiro B, Erffelinck ML, Lacchini E, Ceulemans E, Colinas M, Williams C, Van Hamme E, De Clercq R, Perassolo M, Goossens A

(2022) - Frontiers in plant science

DOI
176. Clustered regularly interspaced short palindromic repeats tools for plant metabolic engineering: achievements and perspectives.

Selma S, Ceulemans E, Goossens A, Lacchini E

(2022) - Current opinion in biotechnology

DOI
175. Interference between ER stress-related bZIP-type and jasmonate-inducible bHLH-type transcription factors in the regulation of triterpene saponin biosynthesis in Medicago truncatula.

Ribeiro B, Erffelinck ML, Lacchini E, Ceulemans E, Colinas M, Williams C, Van Hamme E, De Clercq R, Perassolo M, Goossens A

(2022) - Frontiers in plant science

DOI
174. The basic helix-loop-helix transcription factors MYC1 and MYC2 have a dual role in the regulation of constitutive and stress-inducible specialized metabolism in tomato.

Swinnen G, De Meyer M, Pollier J, Molina-Hidalgo FJ, Ceulemans E, Venegas-Molina J, De Milde L, Fernández-Calvo P, Ron M, Pauwels L, Goossens A

(2022) - The New phytologist

DOI
173. Regulation of jasmonate signaling by reversible acetylation of TOPLESS in Arabidopsis.

An C, Deng L, Zhai H, You Y, Wu F, Zhai Q, Goossens A, Li C

(2022) - Molecular plant

DOI
172. Correction to: Establishment of Proximity-Dependent Biotinylation Approaches in Different Plant Model Systems.

Arora D, Abel NB, Liu C, Van Damme P, Yperman K, Eeckhout D, Vu LD, Wang J, Tornkvist A, Impens F, Korbei B, Van Leene J, Goossens A, De Jaeger G, Van Damme D

(2022) - The Plant cell

DOI
171. Overview of Witloof Chicory (Cichorium intybus L.) Discolorations and Their Underlying Physiological and Biochemical Causes.

De Jaegere I, Cornelis Y, De Clercq T, Goossens A, Van de Poel B

(2022) - Frontiers in plant science

DOI
170. Transient Gene Expression in Catharanthus roseus Flower Petals Using Agroinfiltration.

Colinas M, Goossens A

(2022) - Methods in molecular biology (Clifton, N.J.)

DOI
169. Warm temperature triggers JOX and ST2A-mediated jasmonate catabolism to promote plant growth

Tingting Zhu, Cornelia Herrfurth, Mingming Xin, Tatyana Savchenko, Ivo Feussner, Alain Goossens, Ive De Smet

(2021) - Nature Communications

DOI
168. Dissecting cholesterol and phytosterol biosynthesis via mutants and inhibitors

Kjell De Vriese, Jacob Pollier, Alain Goossens, Tom Beeckman, Steffen Vanneste, John Lunn

(2021) - Journal of Experimental Botany

DOI
167. Engineering Metabolism in Nicotiana Species: A Promising Future

Francisco Javier Molina-Hidalgo, Marta Vazquez-Vilar, Lucio D'Andrea, Olivia C. Demurtas, Paul Fraser, Giovanni Giuliano, Ralph Bock, Diego Orzáez, Alain Goossens

(2021) - Trends in Biotechnology

DOI
166. A network of stress-related genes regulates hypocotyl elongation downstream of selective auxin perception

Adeline Rigal, Siamsa M. Doyle, Andrés Ritter, Sara Raggi, Thomas Vain, José Antonio O’Brien, Alain Goossens, Laurens Pauwels, Stéphanie Robert

(2021) - Plant Physiology

DOI
165. Subfunctionalization of Paralog Transcription Factors Contributes to Regulation of Alkaloid Pathway Branch Choice in Catharanthus roseus.

Colinas M, Pollier J, Vaneechoutte D, Malat DG, Schweizer F, De Milde L, De Clercq R, Guedes JG, Martínez-Cortés T, Molina-Hidalgo FJ, Sottomayor M, Goossens A

(2021) - Frontiers in plant science

DOI
164. Why and How to Dig into Plant Metabolite-Protein Interactions.

Venegas-Molina J, Molina-Hidalgo FJ, Clicque E, Goossens A

(2021) - Trends in plant science

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163. Pathogen Effectors: Exploiting the Promiscuity of Plant Signaling Hubs.

Ceulemans E, Ibrahim HMM, De Coninck B, Goossens A

(2021) - Trends in plant science

DOI
162. The Heat Shock Protein 40-Type Chaperone MASH Supports the Endoplasmic Reticulum-Associated Degradation E3 Ubiquitin Ligase MAKIBISHI1 in Medicago truncatula.

Erffelinck ML, Ribeiro B, Gryffroy L, Rai A, Pollier J, Goossens A

(2021) - Frontiers in plant science

DOI
161. An Independent Evolutionary Origin for Insect Deterrent Cucurbitacins in Iberis amara.

Lemeng Dong, Almeida A, Pollier J, Khakimov B, Bassard JE, Miettinen K, Stærk D, Mehran R, Olsen CE, Motawia MS, Goossens A, Søren Bak

(2021) - Molecular Biology and Evolution

DOI
160. Modulation of Arabidopsis root growth by specialized triterpenes

Yuechen Bai, Patricia Fernández Calvo, Andres Ritter, Ancheng Huang, Stefania Morales, Keylla Bicalho, Michal Karady, Laurens Pauwels, Dieter Buyst, Maria Njo, Karin Ljung, Jose C. Martins, Steffen Vanneste, Tom Beeckman, Anne Osbourn, Alain Goossens, Jacob Pollier

(2021) - New Phytologist

DOI
159. RBR-Type E3 Ligases and the Ubiquitin-Conjugating Enzyme UBC26 Regulate Abscisic Acid Receptor Levels and Signaling

Maria Angeles Fernandez, Borja Belda-Palazon, Jose Julian, Alberto Coego, Jorge Lozano-Juste, Sabrina Iñigo, Lesia Rodriguez, Eduardo Bueso, Alain Goossens, Pedro L. Rodriguez

(2020) - Plant Physiology

DOI
158. Establishment of CRISPR/Cas9 Genome Editing in Witloof (Cichorium intybus var. foliosum).

De Bruyn C, Ruttink T, Eeckhaut T, Jacobs T, De Keyser E, Goossens A, Van Laere K

(2020) - Frontiers in genome editing

DOI
157. Establishment of Proximity-Dependent Biotinylation Approaches in Different Plant Model Systems.

Arora D, Abel NB, Liu C, Van Damme P, Yperman K, Eeckhout D, Vu LD, Wang J, Tornkvist A, Impens F, Korbei B, Van Leene J, Goossens A, De Jaeger G, Van Damme D

(2020) - The Plant cell

DOI
156. The Molecular Basis of JAZ-MYC Coupling, a Protein-Protein Interface Essential for Plant Response to Stressors.

Oña Chuquimarca S, Ayala-Ruano S, Goossens J, Pauwels L, Goossens A, Leon-Reyes A, Ángel Méndez M

(2020) - Frontiers in plant science

DOI
155. A hairy-root transformation protocol for Trigonella foenum-graecum L. as a tool for metabolic engineering and specialised metabolite pathway elucidation.

Garagounis C, Beritza K, Georgopoulou ME, Sonawane P, Haralampidis K, Goossens A, Aharoni A, Papadopoulou KK

(2020) - Plant physiology and biochemistry : PPB

DOI
154. Combinatorial Control of Plant Specialized Metabolism: Mechanisms, Functions, and Consequences.

Lacchini E, Goossens A

(2020) - Annual review of cell and developmental biology

DOI
153. Boosting the Synthesis of Pharmaceutically Active Abietane Diterpenes in S. sclarea Hairy Roots by Engineering the GGPPS and CPPS Genes.

Vaccaro MC, Alfieri M, De Tommasi N, Moses T, Goossens A, Leone A

(2020) - Frontiers in plant science

DOI
152. A Seed-Specific Regulator of Triterpene Saponin Biosynthesis in Medicago truncatula.

Ribeiro B, Lacchini E, Bicalho KU, Mertens J, Arendt P, Arendt P, Vanden Bossche R, Calegario G, Gryffroy L, Ceulemans E, Buitink J, Goossens A, Pollier J

(2020) - The Plant cell

DOI
151. CRISPR-Cas-Mediated Gene Knockout in Tomato.

Swinnen G, Jacobs T, Pauwels L, Goossens A

(2020) - Methods in molecular biology (Clifton, N.J.)

DOI
150. Phytohormones: Multifunctional nutraceuticals against metabolic syndrome and comorbid diseases.

Kim SW, Goossens A, Libert C, Filip Van Immerseel, Jens Staal, Beyaert R

(2020) - Biochemical Pharmacology

DOI
149. Organization and regulation of triterpene saponin biosynthesis in Medicago truncatula

Jan Mertens, Alain Goossens

(2020) - The Model Legume Medicago truncatula

DOI
148. FRS7 and FRS12 recruit NINJA to regulate expression of glucosinolate biosynthesis genes

Patricia Fernández Calvo, Sabrina Iñigo, Gaetan Glauser, robin Vanden Bossche, Michelle Tang, Baohua Li, Rebecca De Clercq, Astrid Nagels Durand, Dominique Eeckhout, Kris Gevaert, Geert De Jaeger, Siobhan Brady, Daniel Kliebenstein, Laurens Pauwels, Alain Goossens, Andres Ritter

(2020) - New Phytologist

DOI
147. CYP712K4 Catalyzes the C-29 Oxidation of Friedelin in the Maytenus ilicifolia Quinone Methide Triterpenoid Biosynthesis Pathway

Keylla U Bicalho, Mariana M Santoni, Philipp Arendt, Cleslei F Zanelli, Maysa Furlan, Alain Goossens, Jacob Pollier

(2019) - Plant and Cell Physiology

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146. Regulatory Oxylipins Anno 2019: Jasmonates Galore in the Plant Oxylipin Research Community.

Goossens A, Farmer EE

(2019) - Plant & cell physiology

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145. A specialized metabolic network selectively modulates Arabidopsis root microbiota

Ancheng C. Huang, Ting Jiang, Yong-Xin Liu, Yue-Chen Bai, James Reed, Baoyuan Qu, Alain Goossens, Hans-Wilhelm Nützmann, Yang Bai, Anne Osbourn

(2019) - Science

DOI
144. Jasmonate and auxin perception: how plants keep F-boxes in check

Clara Williams, Patricia Fernández-Calvo, Maite Colinas, Laurens Pauwels, Alain Goossens

(2019) - Journal of Experimental Botany

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143. A MYC2/MYC3/MYC4-dependent transcription factor network regulates water spray-responsive gene expression and jasmonate levels.

Van Moerkercke A, Duncan O, Zander M, Šimura J, Broda M, Vanden Bossche R, Lewsey MG, Lama S, Singh KB, Ljung K, Ecker JR, Goossens A, Millar AH, Van Aken O

(2019) - Proceedings of the National Academy of Sciences of the United States of America

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142. Lessons from Domestication: Targeting Cis-Regulatory Elements for Crop Improvement.

Swinnen G, Goossens A, Pauwels L

(2019) - Trends in plant science

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141. Jasmonates: what ALLENE OXIDE SYNTHASE does for plants.

Farmer EE, Goossens A

(2019) - Journal of experimental botany

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140. Integrated metabolomics identifies CYP72A67 and CYP72A68 oxidases in the biosynthesis of Medicago truncatula oleanate sapogenins.

Tzin V, Snyder JH, Yang DS, Huhman DV, Watson BS, Allen SN, Tang Y, Miettinen K, Arendt P, Pollier J, Goossens A, Sumner LW

(2019) - Metabolomics : Official journal of the Metabolomic Society

DOI
139. The MYB transcription factor Emission of Methyl Anthranilate 1 stimulates emission of methyl anthranilate from Medicago truncatula hairy roots.

Pollier J, De Geyter N, Moses T, Boachon B, Franco-Zorrilla JM, Bai Y, Lacchini E, Gholami A, Vanden Bossche R, Werck-Reichhart D, Goormachtig S, Goossens A

(2019) - The Plant journal : for cell and molecular biology

DOI
138. Metabolic editing: small measures, great impact.

Swinnen G, Goossens A, Colinas M

(2019) - Current opinion in biotechnology

DOI
137. A Dual sgRNA Approach for Functional Genomics inArabidopsis thaliana

Laurens Pauwels, Rebecca De Clercq, Jonas Goossens, Sabrina Iñigo, Clara Williams, Mily Ron, Anne Britt, Alain Goossens

(2018) - G3 Genes|Genomes|Genetics

DOI
136. A widespread alternative squalene epoxidase participates in eukaryote steroid biosynthesis

Jacob Pollier, Emmelien Vancaester, Unnikrishnan Kuzhiumparambil, Claudia E. Vickers, Klaas Vandepoele, Alain Goossens, Michele Fabris

(2018) - Nature Microbiology

DOI
135. A Single Oxidosqualene Cyclase Produces the Seco-Triterpenoid α-Onocerin

Aldo Almeida, Lemeng Dong, Bekzod Khakimov, Jean-Etienne Bassard, Tessa Moses, Frederic Lota, Alain Goossens, Giovanni Appendino, Søren Bak

(2018) - Plant Physiology

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134. Arabidopsis Leaf Flatness Is Regulated by PPD2 and NINJA through Repression of CYCLIN D3 Genes

Alexandra Baekelandt, Laurens Pauwels, Zhibiao Wang, Na Li, Liesbeth De Milde, Annelore Natran, Mattias Vermeersch, Yunhai Li, Alain Goossens, Dirk Inzé, Nathalie Gonzalez

(2018) - Plant Physiology

DOI
133. A user-friendly platform for yeast two-hybrid library screening using next generation sequencing

Marie-Laure Erffelinck, Alan M. Moses, Bianca Ribeiro, Maria Perassolo, Laurens Pauwels, Jacob Pollier, Veronique Storme, Alain Goossens

(2018) - PLOS ONE

DOI
132. Co-expression of squalene epoxidases with triterpene cyclases boosts production of triterpenoids in plants and yeast.

Dong L, Pollier J, Bassard JE, Ntallas G, Almeida A, Lazaridi E, Khakimov B, Arendt P, de Oliveira LS, Lota F, Goossens A, Michoux F, Bak S

(2018) - Metabolic engineering

DOI
131. Review: Endoplasmic Reticulum-Associated Degradation (ERAD)-Dependent Control of (Tri)terpenoid Metabolism in Plants.

Erffelinck ML, Goossens A

(2018) - Planta medica

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130. An engineered combinatorial module of transcription factors boosts production of monoterpenoid indole alkaloids in Catharanthus roseus.

Schweizer F, Colinas M, Pollier J, Van Moerkercke A, Vanden Bossche R, de Clercq R, Goossens A

(2018) - Metabolic engineering

DOI
129. Author Correction: The transcriptional repressor complex FRS7-FRS12 regulates flowering time and growth in Arabidopsis.

Ritter A, Iñigo S, Fernández-Calvo P, Heyndrickx KS, Dhondt S, Shi H, De Milde L, Bossche RV, De Clercq R, Eeckhout D, Ron M, Somers DE, Inzé D, Goossens A

(2018) - Nature communications

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128. Triterpene Messages from the EU-FP7 Project TriForC.

Goossens A, Osbourn A, Michoux F, Bak S

(2018) - Trends in plant science

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127. STERILE APETALA modulates the stability of a repressor protein complex to control organ size in Arabidopsis thaliana.

Li N, Liu Z, Wang Z, Ru L, Gonzalez N, Baekelandt A, Pauwels L, Goossens A, Xu R, Zhu Z, Inzé D, Li Y

(2018) - PLoS genetics

DOI
126. Combinatorial Transcriptional Control of Plant Specialized Metabolism.

Colinas M, Goossens A

(2018) - Trends in plant science

DOI
125. The TriForC database: a comprehensive up-to-date resource of plant triterpene biosynthesis.

Miettinen K, Iñigo S, Kreft L, Pollier J, De Bo C, Botzki A, Coppens F, Bak S, Goossens A

(2018) - Nucleic acids research

DOI
124. The transcription factor bZIP14 regulates the TCA cycle in the diatom Phaeodactylum tricornutum

Michiel Matthijs, Michele Fabris, Toshihiro Obata, Imogen Foubert, José Manuel Franco‐Zorrilla, Roberto Solano, Alisdair R Fernie, Wim Vyverman, Alain Goossens

(2017) - The EMBO Journal

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123. Strobilurins as growth‐promoting compounds: how Stroby regulates Arabidopsis leaf growth

Judith Van Dingenen, Chrystalla Antoniou, Panagiota Filippou, Jacob Pollier, Nathalie Gonzalez, Stijn Dhondt, Alain Goossens, Vasileios Fotopoulos, Dirk Inzé

(2017) - Plant, Cell & Environment

DOI
122. Synthetic biology approaches for the production of plant metabolites in unicellular organisms

Tessa Moses, Payam Mehrshahi, Alison G Smith, Alain Goossens

(2017) - Journal of Experimental Botany

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121. Abscisic Acid as Pathogen Effector and Immune Regulator.

Lievens L, Pollier J, Goossens A, Beyaert R, Staal J

(2017) - Frontiers in plant science

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120. An endoplasmic reticulum-engineered yeast platform for overproduction of triterpenoids.

Arendt P, Miettinen K, Pollier J, De Rycke R, Callewaert N, Goossens A

(2017) - Metabolic engineering

DOI
119. Identification of Iridoid Glucoside Transporters in Catharanthus roseus.

Larsen B, Fuller VL, Pollier J, Van Moerkercke A, Schweizer F, Payne R, Colinas M, O'Connor SE, Goossens A, Halkier BA

(2017) - Plant & cell physiology

DOI
118. A translational synthetic biology platform for rapid access to gram-scale quantities of novel drug-like molecules.

Reed J, Stephenson MJ, Miettinen K, Brouwer B, Leveau A, Brett P, Goss RJM, Goossens A, O'Connell MA, Osbourn A

(2017) - Metabolic engineering

DOI
117. Plants for human health: greening biotechnology and synthetic biology.

Moses T, Goossens A

(2017) - Journal of experimental botany

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116. The transcriptional repressor complex FRS7-FRS12 regulates flowering time and growth in Arabidopsis.

Ritter A, Iñigo S, Fernández-Calvo P, Heyndrickx KS, Dhondt S, Shi H, De Milde L, Vanden Bossche R, De Clercq R, Eeckhout D, Ron M, Somers DE, Goossens A

(2017) - Nature communications

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115. The ancient CYP716 family is a major contributor to the diversification of eudicot triterpenoid biosynthesis.

Miettinen K, Pollier J, Buyst D, Arendt P, Csuk R, Sommerwerk S, Moses T, Mertens J, Sonawane PD, Pauwels L, Aharoni A, Martins J, Nelson DR, Goossens A

(2017) - Nature communications

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114. Correction: Corrigendum: Plant cholesterol biosynthetic pathway overlaps with phytosterol metabolism

Prashant D. Sonawane, Jacob Pollier, Sayantan Panda, Jedrzej Szymanski, Hassan Massalha, Meital Yona, Tamar Unger, Sergey Malitsky, Philipp Arendt, Laurens Pauwels, Efrat Almekias-Siegl, Ilana Rogachev, Sagit Meir, Pablo D. Cárdenas, Athar Masri, Marina Petrikov, Hubert Schaller, Arthur A. Schaffer, Avinash Kamble, Ashok P. Giri, Alain Goossens, Asaph Aharoni

(2017) - Nature Plants

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113. The Ubiquitin System and Jasmonate Signaling

Astrid Nagels Durand, Laurens Pauwels, Alain Goossens

(2016) - Plants

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112. Redundancy and specificity in jasmonate signalling

Andrea Chini, Selena Gimenez-Ibanez, Alain Goossens, Roberto Solano

(2016) - Current Opinion in Plant Biology

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111. Role and functioning of bHLH transcription factors in jasmonate signalling

Jonas Goossens, Jan Mertens, Alain Goossens

(2016) - Journal of Experimental Botany

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110. Flux balance analysis of primary metabolism in the diatom Phaeodactylum tricornutum.

Kim J, Fabris M, Baart G, Kim MK, Goossens A, Vyverman W, Falkowski PG, Lun DS

(2016) - The Plant journal : for cell and molecular biology

DOI
109. Cloning and Functional Characterization of Cycloartenol Synthase from the Red Seaweed Laurencia dendroidea.

Calegario G, Pollier J, Arendt P, de Oliveira LS, Thompson C, Soares AR, Pereira RC, Goossens A, Thompson FL

(2016) - PloS one

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108. Clade IVa Basic Helix-Loop-Helix Transcription Factors Form Part of a Conserved Jasmonate Signaling Circuit for the Regulation of Bioactive Plant Terpenoid Biosynthesis.

Mertens J, Van Moerkercke A, Vanden Bossche R, Pollier J, Goossens A

(2016) - Plant & cell physiology

DOI
107. Isolation of protein complexes from the model legume Medicago truncatula by tandem affinity purification in hairy root cultures.

Goossens J, De Geyter N, Walton A, Eeckhout D, Mertens J, Pollier J, Fiallos-Jurado J, De Keyser A, De Clercq R, Van Leene J, Gevaert K, De Jaeger G, Goossens A

(2016) - The Plant journal : for cell and molecular biology

DOI
106. The basic helix-loop-helix transcription factor BIS2 is essential for monoterpenoid indole alkaloid production in the medicinal plant Catharanthus roseus.

Van Moerkercke A, Steensma P, Gariboldi I, Espoz J, Purnama PC, Schweizer F, Miettinen K, Vanden Bossche R, De Clercq R, Memelink J, Goossens A

(2016) - The Plant journal : for cell and molecular biology

DOI
105. Glutaredoxin GRXS17 Associates with the Cytosolic Iron-Sulfur Cluster Assembly Pathway.

Iñigo S, Durand AN, Ritter A, Le Gall S, Termathe M, Klassen R, Tohge T, De Coninck B, Van Leene J, De Clercq R, Cammue BP, Fernie AR, Gevaert K, Goossens A

(2016) - Plant physiology

DOI
104. The Arabidopsis Iron-Sulfur Protein GRXS17 is a Target of the Ubiquitin E3 Ligases RGLG3 and RGLG4.

Nagels Durand A, Iñigo S, Ritter A, Iniesto E, De Clercq R, Staes A, Van Leene J, Rubio V, Gevaert K, De Jaeger G, Pauwels L, Goossens A

(2016) - Plant & cell physiology

DOI
103. Saponin determination, expression analysis and functional characterization of saponin biosynthetic genes in Chenopodium quinoa leaves.

Fiallos-Jurado J, Pollier J, Moses T, Arendt P, Barriga-Medina N, Morillo E, Arahana V, de Lourdes Torres M, Goossens A, Leon-Reyes A

(2016) - Plant science : an international journal of experimental plant biology

DOI
102. Jasmonates: signal transduction components and their roles in environmental stress responses.

Goossens J, Fernández-Calvo P, Schweizer F, Goossens A

(2016) - Plant molecular biology

DOI
101. Synthetic biology for production of natural and new-to-nature terpenoids in photosynthetic organisms.

Arendt P, Pollier J, Callewaert N, Goossens A

(2016) - The Plant journal : for cell and molecular biology

DOI
100. GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway.

Cárdenas PD, Sonawane PD, Pollier J, Vanden Bossche R, Dewangan V, Weithorn E, Tal L, Meir S, Rogachev I, Malitsky S, Giri AP, Goossens A, Burdman S, Aharoni A

(2016) - Nature communications

DOI
99. Lessons from Domestication: Targeting Cis-Regulatory Elements for Crop Improvement.

Swinnen G, Goossens A, Pauwels L

(2016) - Trends in plant science

DOI
98. Plant cholesterol biosynthetic pathway overlaps with phytosterol metabolism

Prashant D. Sonawane, Jacob Pollier, Sayantan Panda, Jedrzej Szymanski, Hassan Massalha, Meital Yona, Tamar Unger, Sergey Malitsky, Philipp Arendt, Laurens Pauwels, Efrat Almekias-Siegl, Ilana Rogachev, Sagit Meir, Pablo D. Cárdenas, Athar Masri, Marina Petrikov, Hubert Schaller, Arthur A. Schaffer, Avinash Kamble, Ashok P. Giri, Alain Goossens, Asaph Aharoni

(2016) - Nature Plants

DOI
97. Functional characterization of the Arabidopsis transcription factor bZIP29 reveals its role in leaf and root development

Jelle Van Leene, Jonas Blomme, Shubhada R Kulkarni, Bernard Cannoot, Nancy De Winne, Dominique Eeckhout, Geert Persiau, Eveline Van De Slijke, Leen Vercruysse, Robin Vanden Bossche, Ken S Heyndrickx, Steffen Vanneste, Alain Goossens, Kris Gevaert, Klaas Vandepoele, Nathalie Gonzalez, Dirk Inzé, Geert De Jaeger

(2016) - Journal of Experimental Botany

DOI
96. Transcript profiling of jasmonate‐elicited Taxus cells reveals a β‐phenylalanine‐CoA ligase

Karla Ramírez‐Estrada, Teresa Altabella, Miriam Onrubia, Elisabeth Moyano, Cedric Notredame, Lidia Osuna, Robin Vanden Bossche, Alain Goossens, Rosa M. Cusido, Javier Palazon

(2016) - Plant Biotechnology Journal

DOI
95. Profiling of the Early Nitrogen Stress Response in the Diatom Phaeodactylum tricornutum Reveals a Novel Family of RING-Domain Transcription Factors

Michiel Matthijs, Michele Fabris, Stefan Broos, Wim Vyverman, Alain Goossens

(2016) - Plant Physiology

DOI
94. The bHLH Transcription Factors TSAR1 and TSAR2 Regulate Triterpene Saponin Biosynthesis in Medicago truncatula

Jan Mertens, Jacob Pollier, Robin Vanden Bossche, Irene Lopez-Vidriero, José Manuel Franco-Zorrilla, Alain Goossens

(2016) - Plant Physiology

DOI
93. It's Time for Some "Site"-Seeing: Novel Tools to Monitor the Ubiquitin Landscape in Arabidopsis thaliana.

Walton A, Stes E, Cybulski N, Van Bel M, Iñigo S, Durand AN, Timmerman E, Heyman J, Pauwels L, De Veylder L, Goossens A, De Smet I, Coppens F, Gevaert K

(2016) - The Plant cell

DOI
92. Hypersensitivity of Arabidopsis TAXIMIN1 overexpression lines to light stress is correlated with decreased sinapoyl malate abundance and countered by the antibiotic cefotaxime.

Colling J, Pollier J, Vanden Bossche R, Makunga NP, Pauwels L, Goossens A

(2016) - Plant signaling & behavior

DOI
91. It is easy to get huge candidate gene lists for plant metabolism now, but how to get beyond?

Goossens A

(2015) -

DOI
90. The bHLH transcription factor BIS1 controls the seco-iridoid branch of the monoterpenoid indole alkaloid pathway in Catharanthus roseus

No contributors listed

(2015) - Proceedings of the National Academy of Sciences of the United States of America

DOI
89. Iridoid synthase activity is common among the plant progesterone 5β-reductase family.

Munkert J, Pollier J, Miettinen K, Van Moerkercke A, Payne R, Müller-Uri F, Burlat V, O'Connor SE, Memelink J, Kreis W, Goossens A

(2015) -

DOI
88. The RING E3 Ligase KEEP ON GOING Modulates JASMONATE ZIM-DOMAIN12 Stability.

Pauwels L, Ritter A, Goossens J, Durand AN, Liu H, Gu Y, Geerinck J, Boter M, Boter M, Vanden Bossche R, De Clercq R, Van Leene J, Gevaert K, Goossens A

(2015) - Plant physiology

DOI
87. Developing 3D SEM in a broad biological context.

Kremer A, Saskia Lippens, Bartunkova S, Bob Asselbergh, Cedric Blanpain, Matyas Fendrych, Goossens A, Matthew Holt, Sophie Janssens, Krols M, Larsimont JC, Mc Guire C, Moritz Nowack, Saelens X, Schertel A, Schepens B, Michał Ślęzak, Vincent Timmerman, Clara Theunis, VAN Brempt R, Visser Y, Guérin CJ

(2015) - Journal of Microscopy

DOI
86. Overexpression of theArabidopsis thalianasignalling peptide TAXIMIN1 affects lateral organ development

Janine Colling, Takayuki Tohge, Rebecca De Clercq, Geraldine Brunoud, Teva Vernoux, Alisdair R. Fernie, Nokwanda P. Makunga, Alain Goossens, Laurens Pauwels

(2015) - Journal of Experimental Botany

DOI
85. Change of a conserved amino acid in the MYC2 and MYC3 transcription factors leads to release of JAZ repression and increased activity

Jonas Goossens, Gwen Swinnen, Robin Vanden Bossche, Laurens Pauwels, Alain Goossens

(2015) - New Phytologist

DOI
84. Unraveling the Triterpenoid Saponin Biosynthesis of the African Shrub Maesa lanceolata

Tessa Moses, Jacob Pollier, Ahmad Faizal, Sandra Apers, Luc Pieters, Johan M. Thevelein, Danny Geelen, Alain Goossens

(2015) - Molecular Plant

DOI
83. OSC2 and CYP716A14v2 Catalyze the Biosynthesis of Triterpenoids for the Cuticle of Aerial Organs of Artemisia annua

Tessa Moses, Jacob Pollier, Qian Shen, Sandra Soetaert, James Reed, Marie-Laure Erffelinck, Filip C.W. Van Nieuwerburgh, Robin Vanden Bossche, Anne Osbourn, Johan M. Thevelein, Dieter Deforce, Kexuan Tang, Alain Goossens

(2015) - The Plant Cell

DOI
82. A Repressor Protein Complex Regulates Leaf Growth in Arabidopsis

Nathalie Gonzalez, Laurens Pauwels, Alexandra Baekelandt, Liesbeth De Milde, Jelle Van Leene, Nienke Besbrugge, Ken Heyndrickx, Amparo Cuéllar Pérez, Astrid Nagels Durand, Rebecca De Clercq, Eveline Van De Slijke, robin Vanden Bossche, Dominique Eeckhout, Kris Gevaert, Klaas Vandepoele, Geert De Jaeger, Alain Goossens, Dirk Inzé

(2015) - The Plant Cell

DOI
81. Multilayered Organization of Jasmonate Signalling in the Regulation of Root Growth

Debora Gasperini, Aurore Chételat, Ivan F. Acosta, Jonas Goossens, Laurens Pauwels, Alain Goossens, René Dreos, Esteban Alfonso, Edward E. Farmer

(2015) - PLOS Genetics

DOI
80. Tracking the sterol biosynthesis pathway of the diatom Phaeodactylum tricornutum

Michele Fabris, Michiel Matthijs, Sophie Carbonelle, Tessa Moses, Jacob Pollier, Renaat Dasseville, Gino J. E. Baart, Wim Vyverman, Alain Goossens

(2014) - New Phytologist

DOI
79. Natural product biosynthesis in Medicago species

Azra Gholami, Nathan De Geyter, Jacob Pollier, Sofie Goormachtig, Alain Goossens

(2014) - Natural Product Reports

DOI
78. The Non-JAZ TIFY Protein TIFY8 from Arabidopsis thaliana Is a Transcriptional Repressor

Amparo Cuéllar Pérez, Astrid Nagels Durand, Robin Vanden Bossche, Rebecca De Clercq, Geert Persiau, Saskia C. M. Van Wees, Corné M. J. Pieterse, Kris Gevaert, Geert De Jaeger, Alain Goossens, Laurens Pauwels

(2014) - PLoS ONE

DOI
77. Goossens Involvement of the leaf-specific multidrug and toxic compound extrusion (MATE) transporter Nt-JAT2 in vacuolar sequestration of nicotine in Nicotiana tabacum

No contributors listed

(2014) - PLoS One

DOI
76. It Is Easy to Get Huge Candidate Gene Lists for Plant Metabolism Now, but How to Get Beyond?

Goossens A

(2014) - Molecular plant

DOI
75. Comparative analysis of CYP93E proteins for improved microbial synthesis of plant triterpenoids

Tessa Moses, Johan M. Thevelein, Alain Goossens, Jacob Pollier

(2014) - Phytochemistry

DOI
74. Selection and validation of reference genes for transcript normalization in gene expression studies in Catharanthus roseus

Jacob Pollier, Robin Vanden Bossche, Heiko Rischer, Alain Goossens

(2014) - Plant Physiology and Biochemistry

DOI
73. The seco-iridoid pathway from Catharanthus roseus

Karel Miettinen, Lemeng Dong, Nicolas Navrot, Thomas Schneider, Vincent Burlat, Jacob Pollier, Lotte Woittiez, Sander van der Krol, Raphaël Lugan, Tina Ilc, Robert Verpoorte, Kirsi-Marja Oksman-Caldentey, Enrico Martinoia, Harro Bouwmeester, Alain Goossens, Johan Memelink, Danièle Werck-Reichhart

(2014) - Nature Communications

DOI
72. Taximin, a conserved plant‐specific peptide is involved in the modulation of plant‐specialized metabolism

Miriam Onrubia, Jacob Pollier, Robin Vanden Bossche, Marc Goethals, Kris Gevaert, Elisabet Moyano, Heriberto Vidal‐Limon, Rosa M. Cusidó, Javier Palazón, Alain Goossens

(2014) - Plant Biotechnology Journal

DOI
71. Combinatorial biosynthesis of sapogenins and saponins in Saccharomyces cerevisiae using a C-16α hydroxylase from Bupleurum falcatum

Tessa Moses, Jacob Pollier, Lorena Almagro, Dieter Buyst, Marc Van Montagu, María A. Pedreño, José C. Martins, Johan M. Thevelein, Alain Goossens

(2014) - Proceedings of the National Academy of Sciences

DOI
70. A rational approach to improving the biotechnological production of taxanes in plant cell cultures of Taxus spp.

Rosa M. Cusido, Miriam Onrubia, Ana B. Sabater-Jara, Elisabet Moyano, Mercedes Bonfill, Alain Goossens, M. Angeles Pedreño, Javier Palazon

(2014) - Biotechnology Advances

DOI
69. Bioengineering of plant (tri)terpenoids: from metabolic engineering of plants to synthetic biology in vivo and in vitro

Tessa Moses, Jacob Pollier, Johan M. Thevelein, Alain Goossens

(2013) - New Phytologist

DOI
68. Salicylic Acid Suppresses Jasmonic Acid Signaling Downstream of SCFCOI1-JAZ by Targeting GCC Promoter Motifs via Transcription Factor ORA59

Dieuwertje Van der Does, Antonio Leon-Reyes, Annemart Koornneef, Marcel C. Van Verk, Nicole Rodenburg, Laurens Pauwels, Alain Goossens, Ana P. Körbes, Johan Memelink, Tita Ritsema, Saskia C.M. Van Wees, Corné M.J. Pieterse

(2013) - The Plant Cell

DOI
67. Coronatine, a more powerful elicitor for inducing taxane biosynthesis in Taxus media cell cultures than methyl jasmonate

Miriam Onrubia, Elisabet Moyano, Mercedes Bonfill, Rosa Mª Cusidó, Alain Goossens, Javier Palazón

(2013) - Journal of Plant Physiology

DOI
66. Jasmonate signalling: a copycat of auxin signalling?

No contributors listed

(2013) - Plant, Cell and Environment

DOI
65. Jasmonate signalling: a copycat of auxin signalling?

Pérez AC, Goossens A

(2013) - Plant, cell & environment

DOI
64. CathaCyc, a Metabolic Pathway Database Built from Catharanthus roseus RNA-Seq Data

Alex Van Moerkercke, Michele Fabris, Jacob Pollier, Gino J.E. Baart, Stephane Rombauts, Ghulam Hasnain, Heiko Rischer, Johan Memelink, Kirsi-Marja Oksman-Caldentey, Alain Goossens

(2013) - Plant and Cell Physiology

DOI
63. Transient Expression Assays in Tobacco Protoplasts

Robin Vanden Bossche, Brecht Demedts, Rudy Vanderhaeghen, Alain Goossens

(2013) - Methods in Molecular Biology

DOI
62. The protein quality control system manages plant defence compound synthesis

Jacob Pollier, Tessa Moses, Miguel González-Guzmán, Nathan De Geyter, Saskia Lippens, Robin Vanden Bossche, Peter Marhavý, Anna Kremer, Kris Morreel, Christopher J. Guérin, Aldo Tava, Wieslaw Oleszek, Johan M. Thevelein, Narciso Campos, Sofie Goormachtig, Alain Goossens

(2013) - Nature

DOI
61. Predicting Gene Function from Uncontrolled Expression Variation among Individual Wild-Type Arabidopsis Plants

Dr. Rahul Bhosale, Jeremy B. Jewell, Jens Hollunder, Abraham J.K. Koo, Marnik Vuylsteke, Tom Michoel, Pierre Hilson, Alain Goossens, Gregg A. Howe, John Browse, Steven Maere

(2013) - The Plant Cell

DOI
60. Yeast Two-Hybrid Analysis of Jasmonate Signaling Proteins

Amparo Pérez Cuéllar, Laurens Pauwels, Rebecca De Clercq, Alain Goossens

(2013) - Methods in Molecular Biology

DOI
59. Metabolite Profiling of Plant Tissues by Liquid Chromatography Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Jacob Pollier, Alain Goossens

(2013) - Methods in Molecular Biology

DOI
58. cDNA-AFLP-Based Transcript Profiling for Genome-Wide Expression Analysis of Jasmonate-Treated Plants and Plant Cultures

Janine Colling, Jacob Pollier, Nokwanda P. Makunga, Alain Goossens

(2013) - Methods in Molecular Biology

DOI
57. Analysis of RNA-Seq Data with TopHat and Cufflinks for Genome-Wide Expression Analysis of Jasmonate-Treated Plants and Plant Cultures

Jacob Pollier, Stephane Rombauts, Alain Goossens

(2013) - Methods in Molecular Biology

DOI
56. Differential transcriptome analysis of glandular and filamentous trichomes in Artemisia annua

Sandra SA Soetaert, Christophe MF Van Neste, Mado L Vandewoestyne, Steven R Head, Alain Goossens, Filip CW Van Nieuwerburgh, Dieter LD Deforce

(2013) - BMC Plant Biology

DOI
55. Characterization of a RABE (Ras gene from rat brain E) GTPase expressed during morphogenesis in the unicellular green alga Micrasterias denticulata (zygnematophyceae, streptophyta)

Vannerum K, De Rycke R, Pollier J, Goossens A, Inzé D, Vyverman W

(2012) - Journal of Phycology

DOI
54. Protein–Protein and Protein–Membrane Associations in the Lignin Pathway

Jean-Etienne Bassard, Ludovic Richert, Jan Geerinck, Hugues Renault, Frédéric Duval, Pascaline Ullmann, Martine Schmitt, Etienne Meyer, Jerôme Mutterer, Wout Boerjan, Geert De Jaeger, Yves Mely, Alain Goossens, Danièle Werck-Reichhart

(2012) - The Plant Cell

DOI
53. The metabolic blueprint of Phaeodactylum tricornutum reveals a eukaryotic Entner–Doudoroff glycolytic pathway

Michele Fabris, Michiel Matthijs, Stephane Rombauts, Wim Vyverman, Alain Goossens, Gino J.E. Baart

(2012) - The Plant Journal

DOI
52. Transcriptional machineries in jasmonate-elicited plant secondary metabolism

Nathan De Geyter, Azra Gholami, Sofie Goormachtig, Alain Goossens

(2012) - Trends in Plant Science

DOI
51. A MultiSite GatewayTM vector set for the functional analysis of genes in the model Saccharomyces cerevisiae

Astrid Nagels Durand, Tessa Moses, Rebecca De Clercq, Alain Goossens, Laurens Pauwels

(2012) - BMC Molecular Biology

DOI
50. Oleanolic acid

Jacob Pollier, Alain Goossens

(2012) - Phytochemistry

DOI
49. Evaluation of the Anti-angiogenic Activity of Saponins from Maesa lanceolata by Different Assays

Kenn Foubert, Annelies Breynaert, Mart Theunis, Rita Van Den Bossche, Guido R.Y. De Meyer, André Van Daele, Ahmad Faizal, Alain Goossens, Danny Geelen, Edward M. Conway, Arnold Vlietinck, Luc Pieters, Sandra Apers

(2012) - Natural Product Communications

DOI
48. Transcriptional analysis of cell growth and morphogenesis in the unicellular green alga Micrasterias(Streptophyta), with emphasis on the role of expansin

Katrijn Vannerum, Marie JJ Huysman, Riet De Rycke, Marnik Vuylsteke, Frederik Leliaert, Jacob Pollier, Ursula Lütz-Meindl, Jeroen Gillard, Lieven De Veylder, Alain Goossens, Dirk Inzé, Wim Vyverman

(2011) - BMC Plant Biology

DOI
47. An Integrated PCR Colony Hybridization Approach to Screen cDNA Libraries for Full-Length Coding Sequences

Jacob Pollier, Miguel González-Guzmán, Wilson Ardiles-Diaz, Danny Geelen, Alain Goossens

(2011) - PLoS ONE

DOI
46. The relationship between TXS, DBAT, BAPT and DBTNBT gene expression and taxane production during the development of Taxus baccata plantlets

M. Onrubia, E. Moyano, M. Bonfill, J. Palazón, A. Goossens, R.M. Cusidó

(2011) - Plant Science

DOI
45. The relationship between TXS, DBAT, BAPT and DBTNBT gene expression and taxane production during the development of Taxus baccata plantlets.

No contributors listed

(2011) - Plant Science

DOI
44. Jasmonate signaling involves the abscisic acid receptor PYL4 to regulate metabolic reprogramming in Arabidopsis and tobacco

Petri Lackman, Miguel González-Guzmán, Sofie Tilleman, Inês Carqueijeiro, Amparo Cuéllar Pérez, Tessa Moses, Mitsunori Seo, Yuri Kanno, Suvi T. Häkkinen, Marc C. E. Van Montagu, Johan M. Thevelein, Hannu Maaheimo, Kirsi-Marja Oksman-Caldentey, Pedro L. Rodriguez, Heiko Rischer, Alain Goossens

(2011) - Proceedings of the National Academy of Sciences

DOI
43. Combinatorial biosynthesis in plants: A (p)review on its potential and future exploitation

Jacob Pollier, Tessa Moses, Alain Goossens

(2011) - Natural Product Reports

DOI
42. APETALA2/ETHYLENE RESPONSE FACTOR and basic helix–loop–helix tobacco transcription factors cooperatively mediate jasmonate‐elicited nicotine biosynthesis

Kathleen De Boer, Sofie Tilleman, Laurens Pauwels, Robin Vanden Bossche, Valerie De Sutter, Rudy Vanderhaeghen, Pierre Hilson, John D. Hamill, Alain Goossens

(2011) - The Plant Journal

DOI
41. The JAZ Proteins: A Crucial Interface in the Jasmonate Signaling Cascade

Laurens Pauwels, Alain Goossens

(2011) - The Plant Cell

DOI
40. Metabolite Profiling of Triterpene Saponins in Medicago truncatula Hairy Roots by Liquid Chromatography Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Jacob Pollier, Kris Morreel, Danny Geelen, Alain Goossens

(2011) - Journal of Natural Products

DOI
39. TheArabidopsisbHLH Transcription Factors MYC3 and MYC4 Are Targets of JAZ Repressors and Act Additively with MYC2 in the Activation of Jasmonate Responses

Patricia Fernández-Calvo, Andrea Chini, Gemma Fernández-Barbero, José-Manuel Chico, Selena Gimenez-Ibanez, Jan Geerinck, Dominique Eeckhout, Fabian Schweizer, Marta Godoy, José Manuel Franco-Zorrilla, Laurens Pauwels, Erwin Witters, María Isabel Puga, Javier Paz-Ares, Alain Goossens, Philippe Reymond, Geert De Jaeger, Roberto Solano

(2011) - The Plant Cell

DOI
38. Dissection of the phytohormonal regulation of trichome formation and biosynthesis of the antimalarial compound artemisinin in Artemisia annua plants

Lies Maes, Filip C. W. Van Nieuwerburgh, Yansheng Zhang, Darwin W. Reed, Jacob Pollier, Sofie R. F. Vande Casteele, Dirk Inzé, Patrick S. Covello, Dieter L. D. Deforce, Alain Goossens

(2011) - New Phytologist

DOI
37. Dissection of the one-MegaDalton JAZ1 protein complex.

Geerinck J, Pauwels L, De Jaeger G, Goossens A

(2010) -

DOI
36. Hormone-mediated promotion of trichome initiation in plants is conserved but utilizes species- and trichome-specific regulatory mechanisms.

Maes L, Goossens A

(2010) -

DOI
35. Dissection of the one-MegaDalton JAZ1 protein complex

Jan Geerinck, Laurens Pauwels, Geert De Jaeger, Alain Goossens

(2010) - Plant Signaling & Behavior

DOI
34. NINJA connects the co-repressor TOPLESS to jasmonate signalling

Laurens Pauwels, Gemma Fernández Barbero, Jan Geerinck, Sofie Tilleman, Wim Grunewald, Amparo Cuéllar Pérez, José Manuel Chico, Robin Vanden Bossche, Jared Sewell, Eduardo Gil, Gloria García-Casado, Erwin Witters, Dirk Inzé, Jeff A. Long, Geert De Jaeger, Roberto Solano, Alain Goossens

(2010) - Nature

DOI
33. Vacuolar transport of nicotine is mediated by a multidrug and toxic compound extrusion (MATE) transporter in Nicotiana tabacum

Masahiko Morita, Nobukazu Shitan, Keisuke Sawada, Marc C. E. Van Montagu, Dirk Inzé, Heiko Rischer, Alain Goossens, Kirsi-Marja Oksman-Caldentey, Yoshinori Moriyama, Kazufumi Yazaki

(2009) - Proceedings of the National Academy of Sciences

DOI
32. Cryopreservation of hairy root cultures of Maesa lanceolata and Medicago truncatula.

Lambert E, Goossens A, Panis B, Van Labeke MC, Geelen D

(2009) - Plant Cell, Tissue and Organ Culture

DOI
31. Cryopreservation of hairy root cultures of Maesa lanceolata and Medicago truncatula

E. Lambert, A. Goossens, B. Panis, M. C. Van Labeke, D. Geelen

(2009) - Plant Cell, Tissue and Organ Culture

DOI
30. Jasmonate-inducible gene: what does it mean?

Laurens Pauwels, Dirk Inzé, Alain Goossens

(2009) - Trends in Plant Science

DOI
29. Expression of the Arabidopsis jasmonate signalling repressor JAZ1/TIFY10A is stimulated by auxin

Wim Grunewald, Bartel Vanholme, Laurens Pauwels, Eva Plovie, Dirk Inzé, Godelieve Gheysen, Alain Goossens

(2009) - EMBO reports

DOI
28. Functional Specialization of the TRANSPARENT TESTA GLABRA1 Network Allows Differential Hormonal Control of Laminal and Marginal Trichome Initiation in Arabidopsis Rosette Leaves

Lies Maes, Dirk Inzé, Alain Goossens

(2008) - Plant Physiology

DOI
27. Fine-tuning of early events in the jasmonate response.

Pauwels L, Goossens A

(2008) -

DOI
26. Fine-tuning of early events in the jasmonate response

Laurens Pauwels, Alain Goossens

(2008) - Plant Signaling & Behavior

DOI
25. Mapping methyl jasmonate-mediated transcriptional reprogramming of metabolism and cell cycle progression in cultured Arabidopsis cells

Laurens Pauwels, Kris Morreel, Emilie De Witte, Freya Lammertyn, Marc Van Montagu, Wout Boerjan, Dirk Inzé, Alain Goossens

(2008) - Proceedings of the National Academy of Sciences

DOI
24. The Molecular Cloning of Artemisinic Aldehyde Δ11(13) Reductase and Its Role in Glandular Trichome-dependent Biosynthesis of Artemisinin in Artemisia annua

Yansheng Zhang, Keat H. Teoh, Darwin W. Reed, Lies Maes, Alain Goossens, Douglas J.H. Olson, Andrew R.S. Ross, Patrick S. Covello

(2008) - Journal of Biological Chemistry

DOI
23. Functional characterisation of genes involved in pyridine alkaloid biosynthesis in tobacco

Suvi T. Häkkinen, Sofie Tilleman, Agnieszka Šwiątek, Valerie De Sutter, Heiko Rischer, Isabelle Vanhoutte, Harry Van Onckelen, Pierre Hilson, Dirk Inzé, Kirsi-Marja Oksman-Caldentey

(2007) - Phytochemistry

DOI
22. Implementation of functional genomics for gene discovery in alkaloid producing plants

Alain Goossens, Heiko Rischer

(2007) - Phytochemistry Reviews

DOI
21. Determination of saponins in Maesa lanceolata by LC-UV: Development and validation

Mart H.B.L. Theunis, Kenn Foubert, Jacob Pollier, Miguel Gonzalez-Guzman, Alain Goossens, Arnold J. Vlietinck, Luc A.C. Pieters, Sandra Apers

(2007) - Phytochemistry

DOI
20. Quantitation of artemisinin and its biosynthetic precursors in Artemisia annua L. by high performance liquid chromatography–electrospray quadrupole time-of-flight tandem mass spectrometry

Filip C.W. Van Nieuwerburgh, Sofie R.F. Vande Casteele, Lies Maes, Alain Goossens, Dirk Inzé, Jan Van Bocxlaer, Dieter L.D. Deforce

(2006) - Journal of Chromatography A

DOI
19. Gene-to-metabolite networks for terpenoid indole alkaloid biosynthesis in Catharanthus roseus cells

Heiko Rischer, Matej Orešič, Tuulikki Seppänen-Laakso, Mikko Katajamaa, Freya Lammertyn, Wilson Ardiles-Diaz, Marc C. E. Van Montagu, Dirk Inzé, Kirsi-Marja Oksman-Caldentey, Alain Goossens

(2006) - Proceedings of the National Academy of Sciences

DOI
18. Identification of Four Adenosine Kinase Isoforms in Tobacco By-2 Cells and Their Putative Role in the Cell Cycle-regulated Cytokinin Metabolism

Zuzanna Kwade, Agnieszka Świaątek, Abdelkrim Azmi, Alain Goossens, Dirk Inzé, Harry Van Onckelen, Luc Roef

(2005) - Journal of Biological Chemistry

DOI
17. Exploration of jasmonate signalling via automated and standardized transient expression assays in tobacco cells

Valerie De Sutter, Rudy Vanderhaeghen, Sofie Tilleman, Freya Lammertyn, Isabelle Vanhoutte, Mansour Karimi, Dirk Inzé, Alain Goossens, Pierre Hilson

(2005) - The Plant Journal

DOI
16. A reproducible genetic transformation system for cultivated Phaseolus acutifolius (tepary bean) and its use to assess the role of arcelins in resistance to the Mexican bean weevil.

Zambre M, Goossens A, Cardona C, Van Montagu M, Terryn N, Angenon G

(2005) - Theoretical and Applied Genetics

DOI
15. Methyl jasmonate stimulates the de novo biosynthesis of vitamin C in plant cell suspensions

Beata A. Wolucka, Alain Goossens, Dirk Inzé

(2005) - Journal of Experimental Botany

DOI
14. A functional genomics approach toward the understanding of secondary metabolism in plant cells

Alain Goossens, Suvi T. Häkkinen, Into Laakso, Tuulikki Seppänen-Laakso, Stefania Biondi, Valerie De Sutter, Freya Lammertyn, Anna Maria Nuutila, Hans Söderlund, Marc Zabeau, Dirk Inzé, Kirsi-Marja Oksman-Caldentey

(2003) - Proceedings of the National Academy of Sciences

DOI
13. Secretion of Secondary Metabolites by ATP-Binding Cassette Transporters in Plant Cell Suspension Cultures

Alain Goossens, Suvi T. Häkkinen, Into Laakso, Kirsi-Marja Oksman-Caldentey, Dirk Inzé

(2003) - Plant Physiology

DOI
12. Boosting heterologous protein production in transgenic dicotyledonous seeds using Phaseolus vulgaris regulatory sequences

Geert De Jaeger, Stanley Scheffer, Anni Jacobs, Mukund Zambre, Oliver Zobell, Alain Goossens, Ann Depicker, Geert Angenon

(2002) - Nature Biotechnology

DOI
11. Involvement of Nst1p/YNL091w and Msl1p, a U2B'' splicing factor, in Saccharomyces cerevisiae salt tolerance.

Goossens A, Forment J, Serrano R

(2002) -

DOI
10. Involvement of Nst1p/YNL091w and Msl1p, a U2B″ splicing factor, in Saccharomyces cerevisiae salt tolerance

Alain Goossens, Javier Forment, Ramon Serrano

(2002) - Yeast

DOI
9. The protein kinase Gcn2p mediates sodium toxicity in yeast.

Goossens A, Thomas E Dever, AMPARO PASCUAL-AHUIR, Serrano R

(2001) - The Journal of Biological Chemistry

DOI
8. Regulation of yeast H(+)-ATPase by protein kinases belonging to a family dedicated to activation of plasma membrane transporters.

Goossens A, de La Fuente N, Forment J, Serrano R, Portillo F

(2000) - Molecular and Cellular Biology

DOI
7. Analysis of bruchid resistance in the wild common bean accession G02771: no evidence for insecticidal activity of arcelin 5.

Goossens A, Quintero C, Dillen W, De Rycke R, Valor JF, De Clercq J, Van Montagu M, Cardona C, Geert Angenon

(2000) - Journal of Experimental Botany

DOI
6. Co-introduction of an antisense gene for an endogenous seed storage protein can increase expression of a transgene in Arabidopsis thaliana seeds.

Goossens A, Van Montagu M, Geert Angenon

(1999) - FEBS Letters

DOI
5. The arcelin-5 gene of Phaseolus vulgaris directs high seed-specific expression in transgenic Phaseolus acutifolius and Arabidopsis plants.

Goossens A, Dillen W, De Clercq J, Van Montagu M, Geert Angenon

(1999) - Plant Physiology

DOI
4. Agrobacterium-mediated transformation of Phaseolus acutifolius A. Gray

W. Dillen, J. De Clercq, A. Goossens, M. Van Montagu, G. Angenon

(1997) - Theoretical and Applied Genetics

DOI
3. Crystal structure of arcelin-5, a lectin-like defense protein from Phaseolus vulgaris.

Thomas Hamelryck, Poortmans F, Goossens A, Geert Angenon, Van Montagu M, Wyns L, Remy Loris

(1996) - The Journal of Biological Chemistry

DOI
2. The Electronic Plant Gene Register

No contributors listed

(1995) - Plant Physiology

DOI
1. Isolation and characterisation of arcelin-5 proteins and cDNAs.

Goossens A, Geremia R, Bauw G, Van Montagu M, Geert Angenon

(1994) - European Journal of Biochemistry

DOI